Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure (NCT05677100)
DRAIN-HF: Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
🩺 Plain-English Summary (8th-Grade Level)
Aortix is a circulatory support device for chronic heart failure patients on medical management who have been hospitalized for acute decompensated heart failure (ADHF) and have persistent congestion despite usual medical therapy. Eligible ADHF patients with diuretic resistance (irrespective of ejection fraction) will be enrolled and randomized 1:1 to either the Aortix system or standard of care medical management.
Who can join: Review the eligibility criteria below.
Location: Banner--University Medical Center Phoenix — Phoenix, Arizona
Age range: 21 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (50 Sites)
Showing the first 25 of 50 sites.
- Banner--University Medical Center Phoenix — Phoenix, Arizona
- Mayo Clinic - Arizona — Phoenix, Arizona
- HonorHealth Medical Center — Scottsdale, Arizona
- John Muir Health — Concord, California
- Zuckerberg San Francisco General — San Francisco, California
- San Francisco Veterans Administration — San Francisco, California
- University of California San Francisco — San Francisco, California
- Broward Health — Fort Lauderdale, Florida
- Ascension Sacred Heart — Pensacola, Florida
- Tallahassee Research Institute — Tallahassee, Florida
- University of South Florida — Tampa, Florida
- BayCare Medical/St. Joseph's Hospital — Tampa, Florida
- AdventHealth Tampa — Tampa, Florida
- Cleveland Clinic Florida — Weston, Florida
- Emory University Hospital — Atlanta, Georgia
- Piedmont Healthcare Inc. — Augusta, Georgia
- Wellstar Research Institue — Marietta, Georgia
- University of Chicago — Chicago, Illinois
- Advocate IMMC — Chicago, Illinois
- Advocate Aurora - Good Samaritan — Downers Grove, Illinois
- Ascenscion Alexian Brothers — Elk Grove Village, Illinois
- Ascension via Christi Kansas — Wichita, Kansas
- University of Michigan, Cardiovascular Medicine — Ann Arbor, Michigan
- Henry Ford — Detroit, Michigan
- University of Mississippi Medical Center — Jackson, Mississippi
📞 Contact the Study Coordinator
Phone: (832) 536-1601
Email: rubi@procyrion.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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- Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients — Huntsville, Alabama
- LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. — Birmingham, Alabama
- A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation — Alexander City, Alabama
Explore by condition: All Heart Failure clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.