The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation (NCT05836987)
REACT-AF: Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation
🩺 Plain-English Summary (8th-Grade Level)
REACT-AF is a multicenter prospective, randomized, open-label, blinded endpoint (PROBE design), controlled trial comparing the current Standard Of Care (SOC) of continuous Direct Oral Anticoagulation (DOAC) use versus time-delimited (1 month) DOAC guided by an AF-sensing Smart Watch (AFSW) in participants with a history of paroxysmal or persistent Atrial Fibrillation (AF) and low-to-moderate stroke risk.
Who can join: Review the eligibility criteria below.
Location: Banner University — Phoenix, Arizona
Age range: 22 Years to 85 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (93 Sites)
Showing the first 25 of 93 sites.
- Banner University — Phoenix, Arizona
- University of Southern California - Keck School of Medicine — Los Angeles, California
- University of California Los Angeles (UCLA Health) — Los Angeles, California
- UC Davis Health — Sacramento, California
- Scripps Health — San Diego, California
- Kaiser Permanente — San Francisco, California
- Stanford University — Stanford, California
- University of Colorado — Aurora, Colorado
- South Denver Cardiology Associates, P.C. — Littleton, Colorado
- St. Elizabeth's Medical Center — Washington D.C., District of Columbia
- Medical Faculty Associates George Washington University — Washington D.C., District of Columbia
- BayCare Health Systems — Clearwater, Florida
- University of Florida — Gainesville, Florida
- Mayo Clinic — Jacksonville, Florida
- University of Miami - Leonard S. Miller SOM — Miami, Florida
- Sarasota Memorial Health Care System — Sarasota, Florida
- Cleveland Clinic Florida — Stuart, Florida
- Baycare Health Systems Clearwater — Winter Haven, Florida
- Emory University — Atlanta, Georgia
- Georgia Arrhythmia Consultants and Research Institute — Warner Robins, Georgia
- University of Illinois Chicago — Chicago, Illinois
- Northwestern University — Chicago, Illinois
- Rush University Medical Center — Chicago, Illinois
- University of Chicago — Chicago, Illinois
- Loyola University Chicago — Chicago, Illinois
📞 Contact the Study Coordinator
Phone: (650) 724-6211
Email: sgluhm@stanford.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Atrial Fibrillation
- CHAMPION-AF Clinical Trial — Birmingham, Alabama
- Reversal of Atrial Substrate to Prevent Atrial — Calgary, Alberta
- Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients — Rochester, New York
- REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry — Chandler, Arizona
- Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF) — Cleveland, Ohio
- Liraglutide Effect in Atrial Fibrillation — Miami, Florida
Explore by condition: All Atrial Fibrillation clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.