Strategy for Improving Stroke Treatment Response (NCT05948566)
Strategy for Improving Stroke Treatment Response (SISTER) Trial
🩺 Plain-English Summary (8th-Grade Level)
SISTER is a Phase-II, prospective, randomized, placebo-controlled, blinded, dose finding trial that aims to determine the safety and preliminary efficacy of TS23, a monoclonal antibody against the alpha-2 antiplasmin (a2-AP), in acute ischemic stroke.
Who can join: Review the eligibility criteria below.
Location: University of Alabama Hospital — Birmingham, Alabama
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (52 Sites)
Showing the first 25 of 52 sites.
- University of Alabama Hospital — Birmingham, Alabama
- Banner University Medical Center — Phoenix, Arizona
- Mayo Clinic Phoenix — Phoenix, Arizona
- Banner University Medical Center - Tucson — Tucson, Arizona
- UCSD Health La Jolla — La Jolla, California
- Kaiser Permanente Los Angeles — Los Angeles, California
- Sutter Medical Center — Sacramento, California
- UCSD Medical Center- Hillcrest Hospital — San Diego, California
- Hartford Hospital — Hartford, Connecticut
- Yale New Haven Hospital — New Haven, Connecticut
- Christiana Hospital — Newark, Delaware
- UF Health Shands Hospital — Gainesville, Florida
- Jackson Memorial Hospital — Miami, Florida
- Grady Memorial Hospital — Atlanta, Georgia
- University of Chicago Medical Center — Chicago, Illinois
- University of Iowa Hospitals & Clinics — Iowa City, Iowa
- Baptist Healthcare System, Inc. — Lexington, Kentucky
- University of Louisville Hospital — Louisville, Kentucky
- Brigham and Women's Hospital — Boston, Massachusetts
- Massachusetts General Hospital — Boston, Massachusetts
- M Health Fairview Ridges Hospital — Burnsville, Minnesota
- M Health Fairview Southdale Hospital — Edina, Minnesota
- M Health Fairview University of Minnesota Medical Center — Minneapolis, Minnesota
- United Hospital — Saint Paul, Minnesota
- Barnes Jewish Hospital — St Louis, Missouri
📞 Contact the Study Coordinator
Phone: (973) 668-8644
Email: aragonra@ucmail.uc.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Ischemic Stroke
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- Memantine for Enhanced Stroke Recovery — Salt Lake City, Utah
- Sleep for Stroke Management and Recovery Trial — Birmingham, Alabama
- Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial — Huntsville, Alabama
- A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS) — Stanford, California
- VNS-REHAB At-Home - Post-Market Study for Using the Vivistim System® at Home — Chicago, Illinois
Explore by condition: All Ischemic Stroke clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.