๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-02

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients (NCT06008197)

Randomized Trial to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Heart Failure Patients With Left Ventricular Ejection Fraction Greater Than or Equal to 40% Hospitalized Due to an Episode of Acute Decompensated Heart Failure (REDEFINE-HF)

๐ŸŸข Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Colorado Prevention Center

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.

Who can join: Review the eligibility criteria below.

Location: Birmingham, AL Investigative Site 10012 โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (315 Sites)

Showing the first 25 of 315 sites.

  • Birmingham, AL Investigative Site 10012 โ€” Birmingham, Alabama
  • Fairhope, AL Investigative Site 10004 โ€” Fairhope, Alabama
  • Huntsville, AL Investigative Site 10026 โ€” Huntsville, Alabama
  • Glendale, AZ Investigative Site 10096 โ€” Glendale, Arizona
  • Phoenix, AZ Investigative Site 10115 โ€” Phoenix, Arizona
  • Scottsdale, AZ Investigative Site 10003 โ€” Scottsdale, Arizona
  • Chula Vista, CA Investigative Site 10111 โ€” Chula Vista, California
  • Huntington Beach, CA Investigative Site 10031 โ€” Huntington Beach, California
  • Los Angeles, CA Investigative Site 10089 โ€” Los Angeles, California
  • Sacramento, CA Investigative Site 10024 โ€” Sacramento, California
  • San Francisco, CA Investigative Site 10023 โ€” San Francisco, California
  • Tarzana, CA Investigative Site 10409 โ€” Tarzana, California
  • Van Nuys, CA Investigative Site 10109 โ€” Van Nuys, California
  • West Hills, CA Investigative Site 10013 โ€” West Hills, California
  • Aurora, CO Investigative Site 10001 โ€” Aurora, Colorado
  • Denver, CO Investigative Site 10005 โ€” Denver, Colorado
  • Bradenton, FL Investigative Site 10125 โ€” Bradenton, Florida
  • Brooksville, FL Investigative Site 10077 โ€” Brooksville, Florida
  • Fort Lauderdale, FL Investigative Site 10114 โ€” Fort Lauderdale, Florida
  • Fort Myers, FL Investigative Site 10076 โ€” Fort Myers, Florida
  • Hialeah, FL Investigative Site 10104 โ€” Hialeah, Florida
  • Jacksonville, FL Investigative Site 10028 โ€” Jacksonville, Florida
  • Miami, FL Investigative Site 10105 โ€” Miami, Florida
  • Miami, FL Investigative Site 10040 โ€” Miami, Florida
  • Miramar, FL Investigative Site 10113 โ€” Miramar, Florida

๐Ÿ“ž Contact the Study Coordinator

Phone: (303) 860-9900

Email: info@cpcmed.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

Explore by condition: All Heart Failure clinical trials

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—