๐๏ธ Verified NIH Record โข Updated 2026-08-04
The PEERLESS II Study (NCT06055920)
PEERLESS II: RCT of FlowTriever vs. Anticoagulation Alone in Pulmonary Embolism
๐ต Active, Not Recruiting Observational / Diagnostic ๐ Investigational Drug / Biologic Sponsor: Inari Medical
๐ฉบ Plain-English Summary (8th-Grade Level)
This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE.
Who can join: Review the eligibility criteria below.
Location: UAB Division of Cardiovascular Disease โ Birmingham, Alabama
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (77 Sites)
Showing the first 25 of 77 sites.
- UAB Division of Cardiovascular Disease โ Birmingham, Alabama
- Brookwood Medical Center โ Birmingham, Alabama
- Huntington Memorial Hospital โ Pasadena, California
- University of Colorado, Denver โ Aurora, Colorado
- Yale University โ New Haven, Connecticut
- HCA FL Largo Medical Center โ Largo, Florida
- AdventHealth Orlando โ Orlando, Florida
- Emory University โ Atlanta, Georgia
- Northwestern University โ Chicago, Illinois
- McLaren Greater Lansing โ Lansing, Michigan
- Saint Luke's Hospital of Kansas City โ Kansas City, Missouri
- Mercy Hospital Springfield โ Springfield, Missouri
- Nebraska Medical Center โ Omaha, Nebraska
- Virtua Health โ Camden, New Jersey
- SUNY, The University of Buffalo/Gates Vascular โ Buffalo, New York
- Northwell Health โ New York, New York
- Jamaica Hospital โ Queens, New York
- University of Rochester Medical Center โ Rochester, New York
- Stony Brook University Hospital โ Stony Brook, New York
- Montefiore Medical Center โ The Bronx, New York
- University of Cincinnati Medical Center โ Cincinnati, Ohio
- The Cleveland Clinic Foundation โ Cleveland, Ohio
- Ohio State University - Wexner Medical Center โ Columbus, Ohio
- St. Luke's University Hospital โ Bethlehem, Pennsylvania
- AHN Saint Vincent Hospital โ Erie, Pennsylvania
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Pulmonary Embolism
- Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism โ Birmingham, Alabama
- Novel ฮฑ2-Antiplasmin Inactivation for Lysis of Intravascular Thrombi (NAIL-IT) Trial โ Phoenix, Arizona
- Comparing Electrical Impedance Tomography to Computed Tomographic Angiography โ Loveland, Colorado
- Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PE โ Bay Shore, New York
- Michigan Emergency Department Improvement Collaborative (MEDIC) Alert; Pulmonary Embolism (PE) โ Ann Arbor, Michigan
- Pulmonary Embolism International THrOmbolysis Study-3 โ Linz,
Explore by condition: All Pulmonary Embolism clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.