๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-04

The PEERLESS II Study (NCT06055920)

PEERLESS II: RCT of FlowTriever vs. Anticoagulation Alone in Pulmonary Embolism

๐Ÿ”ต Active, Not Recruiting Observational / Diagnostic ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Inari Medical

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alone for intermediate-risk acute PE.

Who can join: Review the eligibility criteria below.

Location: UAB Division of Cardiovascular Disease โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (77 Sites)

Showing the first 25 of 77 sites.

  • UAB Division of Cardiovascular Disease โ€” Birmingham, Alabama
  • Brookwood Medical Center โ€” Birmingham, Alabama
  • Huntington Memorial Hospital โ€” Pasadena, California
  • University of Colorado, Denver โ€” Aurora, Colorado
  • Yale University โ€” New Haven, Connecticut
  • HCA FL Largo Medical Center โ€” Largo, Florida
  • AdventHealth Orlando โ€” Orlando, Florida
  • Emory University โ€” Atlanta, Georgia
  • Northwestern University โ€” Chicago, Illinois
  • McLaren Greater Lansing โ€” Lansing, Michigan
  • Saint Luke's Hospital of Kansas City โ€” Kansas City, Missouri
  • Mercy Hospital Springfield โ€” Springfield, Missouri
  • Nebraska Medical Center โ€” Omaha, Nebraska
  • Virtua Health โ€” Camden, New Jersey
  • SUNY, The University of Buffalo/Gates Vascular โ€” Buffalo, New York
  • Northwell Health โ€” New York, New York
  • Jamaica Hospital โ€” Queens, New York
  • University of Rochester Medical Center โ€” Rochester, New York
  • Stony Brook University Hospital โ€” Stony Brook, New York
  • Montefiore Medical Center โ€” The Bronx, New York
  • University of Cincinnati Medical Center โ€” Cincinnati, Ohio
  • The Cleveland Clinic Foundation โ€” Cleveland, Ohio
  • Ohio State University - Wexner Medical Center โ€” Columbus, Ohio
  • St. Luke's University Hospital โ€” Bethlehem, Pennsylvania
  • AHN Saint Vincent Hospital โ€” Erie, Pennsylvania

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—