An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis (NCT06398626)
A Multi-Center, Prospective, Non-Interventional Study of Real-World Effectiveness of Etrasimod in Patients With Ulcerative Colitis (ENDEAVOUR-UC)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients with moderate to severe ulcerative colitis. Patients will be treated according to standard of care and will only be included in the study if etrasimod is the best treatment of choice according to the physician and they have not previously taken etrasimod. All patients will be prescribed etrasimod according to standard of care. Tests and doctor visits will be conducted according to standard of care with the exception of health questionnaires about ulcerative colitis symptoms. These questionnaires will be completed by patients at various timepoints during the study using their mobile phone, tablet, or computer. The study is 52 weeks with 28 days of safety follow up. The effects of etrasimod will be analyzed for each patient comparing their disease activity prior to the start of etrasimod.
Who can join: Review the eligibility criteria below.
Location: Reddy GI Associates — Mesa, Arizona
Age range: 18 Years to 64 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (28 Sites)
Showing the first 25 of 28 sites.
- Reddy GI Associates — Mesa, Arizona
- Scripps Clinic Torrey Pines — La Jolla, California
- United Medical Doctors — Los Alamitos, California
- United Medical Doctors — Los Alamitos, California
- Rocky Mountain Gastroenterology — Littleton, Colorado
- Digestive and Liver Center of Florida Kissimmee — Kissimmee, Florida
- Gastro Florida — Lutz, Florida
- Orlando Health/Digestive Health Institute — Orlando, Florida
- Feinberg School of Medicine Northwestern University — Chicago, Illinois
- Rush University Medical Center — Chicago, Illinois
- Suburban Gastroenterology Ltd — Naperville, Illinois
- MGG Group Co., Inc., Chevy Chase Clinical Research — Chevy Chase, Maryland
- Woodholme Gastroenterology Associates PA — Glen Burnie, Maryland
- Virtua Health — Marlton, New Jersey
- NYU Langone Health — New York, New York
- Lenox Hill Hospital, Northwell Health — New York, New York
- University of North Carolina at Chapel Hill, Division of Gastroenterology and Hepatology — Chapel Hill, North Carolina
- OnSite Clinical Solutions, LLC — Charlotte, North Carolina
- University of Cincinnati College of Medicine — Cincinnati, Ohio
- Gastro Intestinal Research Institute of Northern Ohio, LLC — Westlake, Ohio
- Medical University of South Carolina (MUSC) — Charleston, South Carolina
- Houston Endoscopy & Research Center — Houston, Texas
- BI Research Center — Houston, Texas
- Brooke Army Medical center — San Antonio, Texas
- Brooke Army Medical center — San Antonio, Texas
📞 Contact the Study Coordinator
Phone: (800) 718-1021
Email: ClinicalTrials.gov_Inquiries@pfizer.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Colitis, Ulcerative
- A Study of Guselkumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis — Oakland, California
- A Study of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis — Arcadia, California
- A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis — Litchfield Park, Arizona
- Determination of the Optimal Treatment Target in Ulcerative Colitis — Ypsilanti, Michigan
- A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis — Kelowna, British Columbia
- A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis — San Francisco, California
Explore by condition: All Colitis, Ulcerative clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.