A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5) (NCT06947941)

🧪 Interventions in This Study

• KarXT (DRUG)
• KarX-EC (DRUG)
• KarXT + KarX-EC Arm Matching Placebo (DRUG)

Full eligibility criteria are available on the official NIH protocol. View the criteria ↗

📍 All Participating Trial Locations (22 Sites)

• Gilbert Neurology Partners/CCT Research — Gilbert, Arizona
• Inland Psychiatric Medical Group. — Chino, California
• Local Institution - 0001 — Naples, Florida
• Local Institution - 1401 — Naples, Florida
• Local Institution - 0029 — Cleveland, Ohio
• Insight Clinical Trials LLC - Independence — Independence, Ohio
• Local Institution - 0020 — Macquarie Park, New South Wales
• Local Institution - 0052 — Nedlands, Western Australia
• Local Institution - 0054 — Toronto, Ontario
• Local Institution - 0027 — Whitby, Ontario
• Local Institution - 0025 — Montreal, Quebec
• Local Institution - 0040 — Suita, Osaka
• Local Institution - 0035 — Nankoku-shi,
• Local Institution - 0034 — Osaka,
• Local Institution - 0005 — Exeter, Devon
• Local Institution - 0023 — London, England
• Local Institution - 0015 — Oxford, Oxfordshire
• Local Institution - 0009 — Chertsey, Surrey
• Local Institution - 0017 — Sheffield, Yorkshire and the Humber
• Local Institution - 0018 — Crowborough,
• Local Institution - 0024 — London,
• Local Institution - 0004 — Motherwell,

📞 Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

💰 Cost, Insurance & Patient Rights

• 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
• Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
• Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

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💡 How to Participate

1. Check the checklist above to see if you may qualify.
2. Contact the study coordinator using the phone/email above.
3. Ask about the visit schedule, what is covered at no cost, and any travel support.
4. Confirm with your own doctor before making a decision.