A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy (NCT06979362)
Phase 2, Multicentre, Randomised, Double-blind, Placebo-controlled Safety and Efficacy Study of CDR132L on Reverse Cardiac Remodelling in Participants With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
🩺 Plain-English Summary (8th-Grade Level)
This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by chance. The study will last for about 60 weeks.
Who can join: Review the eligibility criteria below.
Location: Univ of Alabama Birmingham — Birmingham, Alabama
Age range: 40 Years to 84 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (117 Sites)
Showing the first 25 of 117 sites.
- Univ of Alabama Birmingham — Birmingham, Alabama
- TMC Hlthcr Clin Res Office — Tucson, Arizona
- Pima Heart and Vascular — Tucson, Arizona
- Valley Clinical Trials — Covina, California
- UCSD NAFLD Research Center — La Jolla, California
- Valley Clinical Trials — Northridge, California
- University of California, San Francisco — San Francisco, California
- University of California San Francisco UCSF — San Francisco, California
- Harbor-UCLA Medical Center — Torrance, California
- Univ of Colorado at Denver — Aurora, Colorado
- Inpatient Research Clinic LLC — Miami Lakes, Florida
- AdventHealth Orlando — Orlando, Florida
- Guardian Research Org LLC — Winter Park, Florida
- UofL Health Care Outpatient — Louisville, Kentucky
- Henry Ford Hospital_Detroit — Detroit, Michigan
- University of Minnesota_Minneapolis_1 — Minneapolis, Minnesota
- Washington University School of Medicine — St Louis, Missouri
- Icahn Sch of Med-Mt Sinai Hosp — New York, New York
- Duke University — Durham, North Carolina
- Providence St. Vincent Heart — Portland, Oregon
- Abington Memorial Hospital — Abington, Pennsylvania
- Capital Area Research LLC — Camp Hill, Pennsylvania
- Vanderbilt University Medical Center — Nashville, Tennessee
- Amarillo Medical Specialists — Amarillo, Texas
- University of Texas Southwestern Medical Center — Dallas, Texas
📞 Contact the Study Coordinator
Phone: (866) 867-7178
Email: clinicaltrials@novonordisk.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Heart Failure
- REDUCE LAP-HFREF TRIAL — New York, New York
- Physiological Effects Ketone Ester in Heart — Cleveland, Ohio
- DASH Diet in Heart Failure Outpatients — Sacramento, California
- Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients — Huntsville, Alabama
- LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. — Birmingham, Alabama
- A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation — Alexander City, Alabama
Explore by condition: All Heart Failure clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.