A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF) (NCT06991257)
A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AN ORAL BRANCHED-CHAIN KETOACID DEHYDROGENASE KINASE INHIBITOR, PF-07328948, IN ADULTS WITH HEART FAILURE (BRANCH-HF)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to learn about the safety and effects of the study medicine (PF-07328948) for the possible treatment of heart failure (HF).
Who can join: Review the eligibility criteria below.
Location: National Heart Institute — Beverly Hills, California
Age range: 18 Years to 79 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (142 Sites)
Showing the first 25 of 142 sites.
- National Heart Institute — Beverly Hills, California
- Orange County Research Center — Lake Forest, California
- Comprehensive Cardiovascular Care — Santa Maria, California
- FOMAT Medical Research — Santa Maria, California
- FWD Clinical Research — Boca Raton, Florida
- Jacksonville Center for Clinical Research — Jacksonville, Florida
- Infinite Clinical Research — Miami, Florida
- Flourish Research Acquisition, LLC dba Flourish Research - North Miami — Miami, Florida
- Amavita Research Services — North Miami Beach, Florida
- Clinical Site Partners, LLC dba Flourish Research — Winter Park, Florida
- NMH Clinical Research Unit — Chicago, Illinois
- Northwestern Memorial HealthCare - Arkes Pavilion — Chicago, Illinois
- Northwestern Memorial HealthCare - Feinberg Pavilion — Chicago, Illinois
- Northwestern Memorial HealthCare - Galter Pavilion — Chicago, Illinois
- Northwestern Memorial Hospital Investigational Drug Service (IDS) — Chicago, Illinois
- Northwestern University — Evanston, Illinois
- Chicago Medical Research — Hazel Crest, Illinois
- NexGen Research — Fort Wayne, Indiana
- Reid Physician Associates — Richmond, Indiana
- Ascension Saint Agnes Heart Care — Baltimore, Maryland
- Chesapeake Cardiac Care — Bowie, Maryland
- Flourish Research - Bowie — Bowie, Maryland
- Velocity Clinical Research, Lincoln, Pioneer Heart Institute — Lincoln, Nebraska
- NexGen Research — Lima, Ohio
- Headlands Horizons, LLC dba Headlands Research-Brownsville — Brownsville, Texas
📞 Contact the Study Coordinator
Phone: (800) 718-1021
Email: ClinicalTrials.gov_Inquiries@pfizer.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Heart Failure
- REDUCE LAP-HFREF TRIAL — New York, New York
- Physiological Effects Ketone Ester in Heart — Cleveland, Ohio
- DASH Diet in Heart Failure Outpatients — Sacramento, California
- Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients — Huntsville, Alabama
- LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System. — Birmingham, Alabama
- A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation — Alexander City, Alabama
Explore by condition: All Heart Failure clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.