Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring (NCT07060716)
GraftAssureDx Study: Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring
🩺 Plain-English Summary (8th-Grade Level)
The goal of this observational study is to learn if the donor-derived cell-free DNA (dd-cfDNA) test can assess rejection in kidney transplant recipients. Participants will have blood and urine collected at their study visit. Researchers will compare results of the GraftAssureDx to rejection detected by standard-of-care graft biopsies.
Who can join: Review the eligibility criteria below.
Location: University of Southern California Keck School of Medicine — Los Angeles, California
Age range: 18 Years
🧪 Interventions in This Study
- donor-derived cell-free DNA test (DIAGNOSTIC_TEST)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (10 Sites)
- University of Southern California Keck School of Medicine — Los Angeles, California
- Mayo Clinic in Florida — Jacksonville, Florida
- Tampa General Hospital — Tampa, Florida
- Cleveland Clinic — Cleveland, Ohio
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania
- Vanderbilt University Medical Center — Nashville, Tennessee
- Baylor, Scott & White Research Institute — Dallas, Texas
- Intermountain Health — Murray, Utah
- Institute of Immunology - Transplantation Immunology — Heidelberg, Baden-Wurttemberg
- Charite Universitatsmedizin — Berlin,
📞 Contact the Study Coordinator
Phone: (443) 625-8427
Email: rrogers@imdxinc.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Kidney Transplant Rejection
- Microbiome and Immunosuppression: The Mission Study — Minneapolis, Minnesota
- Validation of Genomic Immune-phenotyping Profiles to Predict Risk of Kidney Transplant Rejection — Chicago, Illinois
- The PROspera Kidney Transplant ACTIVE Rejection Assessment Registry (ProActive) — Birmingham, Alabama
- PROACT Pilot Trial — Vancouver, British Columbia
- AIIM Trial: Personalized Medicine Approach to Kidney Allograft Function — Gainesville, Florida
- Trifecta-Kidney cfDNA-MMDx Study — Tampa, Florida
Explore by condition: All Kidney Transplant Rejection clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.