A Phase 2 Study to Evaluate Povetacicept in Adults With Generalized Myasthenia Gravis (NCT07501702)
A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study With a Long-term Extension of Povetacicept in Adults With Generalized Myasthenia Gravis
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this study is to evaluate the pharmacodynamic (PD) effect, safety, and tolerability of Povetacicept in participants with generalized myasthenia gravis (gMG).
Who can join: Review the eligibility criteria below.
Location: Tri Valley Neurology Medical Associates Inc. — Mission Hills, California
Age range: 18 Years to 80 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (26 Sites)
Showing the first 25 of 26 sites.
- Tri Valley Neurology Medical Associates Inc. — Mission Hills, California
- Neurology Offices — Boca Raton, Florida
- SFM Clinical Reseach, LLC — Boca Raton, Florida
- Homestead Associates in Research — Homestead, Florida
- UF Health Jacksonville Respiratory Therapy (PFT and DLCO) — Jacksonville, Florida
- Y & L Advance Health Care, Inc D/B/A Elite Clinical Research - Neurology — Miami, Florida
- Quantix Research — Miami, Florida
- Hawaii Pacific Neuroscience — Honolulu, Hawaii
- HSHS Medical Group - St. Elizabeth's Hospital — O'Fallon, Illinois
- Las Vegas Neurology Center — Las Vegas, Nevada
- Clinical Trials of South Carolina - Neurology — Charleston, South Carolina
- Ut Erlanger Neurology — Chattanooga, Tennessee
- Nerve and Muscle Center of Texas - Neurology — Houston, Texas
- Texas Institute for Neurological Disorders — Sherman, Texas
- Neurology Care Clinic — Waxahachie, Texas
- Eastern Health - Box Hill Hospital — Box Hill,
- MICS Centrum Medyczne Bydgoszcz — Bydgoszcz,
- Neurologia Slaska Centrum Medyczne — Katowice,
- Clinical Research Center Sp. z o.o., Medic-R Sp. K. — Poznan,
- NZOZ NEURO-KARD Ilkowski i Partnerzy Sp. Partnerska Lekarzy — Poznan,
- Twoja Przychodnia Poznanskie Centrum Medyczne Sp. z o. o. — Poznan,
- Centrum Medyczne Neuroprotect — Warsaw,
- ETG Neuroscience — Warsaw,
- University Hospitals Birmingham NHS Foundation Trust - Queen Elizabeth Hospital — Birmingham,
- St. George's University Hospital — London,
📞 Contact the Study Coordinator
Phone: (617) 341-6777
Email: medicalinfo@vrtx.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Myasthenia Gravis, Generalized
- Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) — Carlsbad, California
- A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC) — Phoenix, Arizona
- Study of Aritinercept in Patients With Generalized Myasthenia Gravis — Pasadena, California
- A Phase 3 Study to Evaluate Claseprubart in Adults With Generalized Myasthenia Gravis (EMERGE) — Boca Raton, Florida
Explore by condition: All Myasthenia Gravis, Generalized clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.