๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-06

A Study of LY3439539 in Participants With Alzheimer's Disease (NCT07598370)

A Phase 1, Open Label, Multiple-Dose Study to Assess the Changes in Cerebrospinal Fluid Biomarkers for Alzheimer's Disease Following Treatment With LY3439539 in Participants With Symptomatic Alzheimer's Disease

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to see how LY3439539 affects certain proteins found in the spinal fluid of participants with Alzheimer's disease. Participation in the study will last approximately 9 months with visits about once a month.

Who can join: Review the eligibility criteria below.

Location: Irvine Clinical Research โ€” Irvine, California

Age range: 50 Years to 85 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (8 Sites)

  • Irvine Clinical Research โ€” Irvine, California
  • Flinders Medical Centre โ€” Adelaide,
  • Austin Health - Heidelberg Repatriation Hospital โ€” Ivanhoe,
  • Southern Neurology โ€” Kogarah,
  • Macquarie University Hospital โ€” Macquarie University,
  • The Alfred โ€” Melbourne,
  • Christchurch Neurology Trials โ€” Christchurch,
  • Lilly Centre for Clinical Pharmacology โ€” Singapore,

๐Ÿ“ž Contact the Study Coordinator

Phone: (317) 615-4559

Email: LillyTrials@Lilly.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—