๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-01-19

A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer (NCT02152631)

JUNIPER: A Randomized Phase 3 Study of Abemaciclib Plus Best Supportive Care Versus Erlotinib Plus Best Supportive Care in Patients With Stage IV NSCLC With a Detectable KRAS Mutation Who Have Progressed After Platinum-Based Chemotherapy

๐Ÿ”ต Active, Not Recruiting Phase3 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Eli Lilly and Company

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.

Who can join: Review the eligibility criteria below.

Location: Highlands Oncology Group โ€” Fayetteville, Arkansas

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (231 Sites)

Showing the first 25 of 231 sites.

  • Highlands Oncology Group โ€” Fayetteville, Arkansas
  • St. Bernards Medical Center โ€” Jonesboro, Arkansas
  • City of Hope National Medical Center โ€” Duarte, California
  • University of California - San Diego โ€” La Jolla, California
  • Loma Linda University School of Medicine โ€” Loma Linda, California
  • CBCC Global Research, Inc. โ€” Los Angeles, California
  • Central Coast Medical Oncology Corporation โ€” Los Angeles, California
  • Fort Wayne Oncology & Hematology โ€” Los Angeles, California
  • SMO TRIO -Translational Research โ€” Los Angeles, California
  • St. Joseph Heritage Medical Group โ€” Los Angeles, California
  • UCLA Department of Medicine-Hematology/Oncology โ€” Los Angeles, California
  • Cancer Care Associates Medical Group โ€” Los Angeles, California
  • Dignity Health Care Institute โ€” Sacramento, California
  • Alegent Immanuel Cancer Center โ€” Englewood, Colorado
  • Jewish Hospital โ€” Englewood, Colorado
  • Oncology Hematology West โ€” Englewood, Colorado
  • SMO Catholic Health Initiatives โ€” Englewood, Colorado
  • St Joseph Cancer Center โ€” Englewood, Colorado
  • St. Francis Medical Center โ€” Englewood, Colorado
  • Medical Oncology Hematology Consultants โ€” Newark, Delaware
  • Boca Raton Regional Hospital โ€” Boca Raton, Florida
  • Halifax Medical Center โ€” Daytona Beach, Florida
  • Memorial Cancer Institute โ€” Pembroke Pines, Florida
  • H Lee Moffitt Cancer Center โ€” Tampa, Florida
  • University Cancer & Blood Center, LLC โ€” Athens, Georgia

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Review the official NIH record below to find the coordinating site.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—