🏛️ Verified NIH Record • Updated 2025-01-07
Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance (NCT04230499)
Phase IIA Trial of Encapsulated Rapamycin (eRapa) to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic Sponsor: Rapamycin Holdings Inc.
🩺 Plain-English Summary (8th-Grade Level)
Patients with Familial Adenomatous Polyposis (FAP) who are undergoing endoscopic surveillance will be given Encapsulated Rapamycin (eRapa) at one of three escalating doses/schedules for 12 months with the aim of reducing polyp burden.
Who can join: Review the eligibility criteria below.
Location: Michigan Medicine — Ann Arbor, Michigan
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (4 Sites)
- Michigan Medicine — Ann Arbor, Michigan
- Cleveland Clinic — Cleveland, Ohio
- Ohio State University — Columbus, Ohio
- UT Health — San Antonio, Texas
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Familial Adenomatous Polyposis
- A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis — Houston, Texas
- A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy — Houston, Texas
- Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) — Ann Arbor, Michigan
- Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) — Scottsdale, Arizona
Explore by condition: All Familial Adenomatous Polyposis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Review the official NIH record below to find the coordinating site.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.