๐๏ธ Verified NIH Record โข Updated 2026-06-03
Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) (NCT05552755)
A Phase 1b-2, Multicenter, Trial to Evaluate the Efficacy, Safety, Pharmacokintetics, and Pharmacodynamics of REC-4881 in Patients With Familial Adenomatous Polyposis (FAP)
๐ข Recruiting Phase1 / Phase2 ๐ Investigational Drug / Biologic Sponsor: Recursion Pharmaceuticals Inc.
๐ฉบ Plain-English Summary (8th-Grade Level)
This is a multicenter, two-part trial in participants with FAP.
Who can join: Review the eligibility criteria below.
Location: Mayo Clinic - Scottsdale โ Scottsdale, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (17 Sites)
- Mayo Clinic - Scottsdale โ Scottsdale, Arizona
- Del Sol Research Management โ Tucson, Arizona
- Medical Associates Research Group โ San Diego, California
- GI Pros โ Naples, Florida
- Digestive and Liver Center of Florida โ Orlando, Florida
- Gastroenterology Health Partners, PLLC โ New Albany, Indiana
- Tandem Clinical Research โ Marrero, Louisiana
- Corewell Health (Spectrum Health Hospitals Colorectal Cancer Multis) โ Grand Rapids, Michigan
- Mayo Clinic - Rochester โ Rochester, Minnesota
- Washington University School of Medicine โ St Louis, Missouri
- University of Pennsylvania โ Philadelphia, Pennsylvania
- Gastro One-8110 Walnut Rs โ Cordova, Tennessee
- Vanderbilt Digestive Center โ Nashville, Tennessee
- Genetic Cancer Prevention Clinic - UT Southwestern โ Dallas, Texas
- MD Anderson Cancer Center โ Houston, Texas
- Huntsman Cancer Institute and University of Utah โ Salt Lake City, Utah
- Benaroya Research Institute at Virginia Mason โ Seattle, Washington
๐ Contact the Study Coordinator
Phone: (385) 374-1724
Email: clinicaltrials@recursion.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Familial Adenomatous Polyposis
- Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance โ Ann Arbor, Michigan
- A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis โ Houston, Texas
- A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy โ Houston, Texas
- Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) โ Ann Arbor, Michigan
Explore by condition: All Familial Adenomatous Polyposis clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.