Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) (NCT06641310)
Phase 1a/b Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP)
🩺 Plain-English Summary (8th-Grade Level)
The purpose of this phase 1a/b trial is to find out what amount of exercise would be best to use for preventing recurrence of colorectal polyps. It involves following one of four different amounts of exercise regimens on a treadmill for 26 weeks. A treadmill will be placed in each study participant's home for the duration of the study. The exercise regimen will be personalized for each participant and monitored remotely by exercise personnel. The in-person study visits occur during the usual standard of care endoscopy exam and during a follow-up exam that is 26 weeks later. Small rectal tissue biopsies, about the size of a grain of rice, will be taken before and after 26 weeks of exercise. The study visits also involve questionnaires, a stool sample, and a blood sample. This study will inform the design of larger, future trials to investigate whether or not recurrence of polyps can be achieved with exercise.
Who can join: Review the eligibility criteria below.
Location: University of Michigan Rogel Cancer Center — Ann Arbor, Michigan
Age range: 18 Years
🧪 Interventions in This Study
- Exercise Therapy (PROCEDURE)
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (2 Sites)
- University of Michigan Rogel Cancer Center — Ann Arbor, Michigan
- Cleveland Clinic Foundation — Cleveland, Ohio
📞 Contact the Study Coordinator
Phone: (734) 763-1141
Email: KLtuck@med.umich.edu
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Familial Adenomatous Polyposis
- Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance — Ann Arbor, Michigan
- A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis — Houston, Texas
- A Personalized Surveillance and Intervention Protocol for Patients With Familial Adenomatous Polyposis That Have Undergone (Procto)Colectomy — Houston, Texas
- Evaluate REC-4881 in Participants With Familial Adenomatous Polyposis (FAP) — Scottsdale, Arizona
Explore by condition: All Familial Adenomatous Polyposis clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.