๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-06-01

A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors (NCT05981703)

A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of HPK1 Inhibitor BGB-26808 Alone or in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: BeOne Medicines

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is an open-label, multicenter, and nonrandomized dose escalation and dose expansion study to evaluate BGB-26808 as monotherapy or in combination with tislelizumab in participants with advanced solid tumors. The main purpose of this study is to explore the recommended dosing for BGB-26808.

Who can join: Review the eligibility criteria below.

Location: City of Hope National Medical Center โ€” Duarte, California

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (28 Sites)

Showing the first 25 of 28 sites.

  • City of Hope National Medical Center โ€” Duarte, California
  • University of Southern California Norris Comprehensive โ€” Los Angeles, California
  • Yale University Yale Cancer Center โ€” New Haven, Connecticut
  • Sylvester Cancer Center, University of Miami โ€” Miami, Florida
  • University of Michigan Health System โ€” Ann Arbor, Michigan
  • John Theurer Cancer Center Hackensack University Medical Center โ€” Hackensack, New Jersey
  • Icahn School of Medicine At Mount Sinai โ€” New York, New York
  • Providence Portland Medical Center โ€” Portland, Oregon
  • The University of Texas Md Anderson Cancer Center โ€” Houston, Texas
  • Southside Cancer Care โ€” Miranda, New South Wales
  • Macquarie University โ€” North Ryde, New South Wales
  • Icon Cancer Centre Kurralta Park โ€” Kurralta Park, South Australia
  • Linear Clinical Research โ€” Nedlands, Western Australia
  • The First Affiliated Hospital of Anhui Medical Universitygaoxin Branch โ€” Hefei, Anhui
  • Harbin Medical University Cancer Hospital โ€” Harbin, Heilongjiang
  • Hubei Cancer Hospital โ€” Wuhan, Hubei
  • Tongji Hospital,Tongji Medical College of Hustsino French New City Branch โ€” Wuhan, Hubei
  • The First Hospital of China Medical University Hunnan Branch โ€” Shenyang, Liaoning
  • Jining No1 Peoples Hospital West Branch โ€” Jining, Shandong
  • Yantai Yuhuangding Hospital โ€” Yantai, Shandong
  • Shanghai East Hospital Branch Hospital โ€” Shanghai, Shanghai Municipality
  • Shanghai Pulmonary Hospital โ€” Shanghai, Shanghai Municipality
  • Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital โ€” Chengdu, Sichuan
  • Hangzhou First Peoples Hospital โ€” Hangzhou, Zhejiang
  • Taizhou Hospital of Zhejiang Province (East) โ€” Taizhou, Zhejiang

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 828-5568

Email: clinicaltrials@beonemed.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—