A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors (NCT05981703)
A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of HPK1 Inhibitor BGB-26808 Alone or in Combination With Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
This is an open-label, multicenter, and nonrandomized dose escalation and dose expansion study to evaluate BGB-26808 as monotherapy or in combination with tislelizumab in participants with advanced solid tumors. The main purpose of this study is to explore the recommended dosing for BGB-26808.
Who can join: Review the eligibility criteria below.
Location: City of Hope National Medical Center โ Duarte, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (28 Sites)
Showing the first 25 of 28 sites.
- City of Hope National Medical Center โ Duarte, California
- University of Southern California Norris Comprehensive โ Los Angeles, California
- Yale University Yale Cancer Center โ New Haven, Connecticut
- Sylvester Cancer Center, University of Miami โ Miami, Florida
- University of Michigan Health System โ Ann Arbor, Michigan
- John Theurer Cancer Center Hackensack University Medical Center โ Hackensack, New Jersey
- Icahn School of Medicine At Mount Sinai โ New York, New York
- Providence Portland Medical Center โ Portland, Oregon
- The University of Texas Md Anderson Cancer Center โ Houston, Texas
- Southside Cancer Care โ Miranda, New South Wales
- Macquarie University โ North Ryde, New South Wales
- Icon Cancer Centre Kurralta Park โ Kurralta Park, South Australia
- Linear Clinical Research โ Nedlands, Western Australia
- The First Affiliated Hospital of Anhui Medical Universitygaoxin Branch โ Hefei, Anhui
- Harbin Medical University Cancer Hospital โ Harbin, Heilongjiang
- Hubei Cancer Hospital โ Wuhan, Hubei
- Tongji Hospital,Tongji Medical College of Hustsino French New City Branch โ Wuhan, Hubei
- The First Hospital of China Medical University Hunnan Branch โ Shenyang, Liaoning
- Jining No1 Peoples Hospital West Branch โ Jining, Shandong
- Yantai Yuhuangding Hospital โ Yantai, Shandong
- Shanghai East Hospital Branch Hospital โ Shanghai, Shanghai Municipality
- Shanghai Pulmonary Hospital โ Shanghai, Shanghai Municipality
- Sichuan Academy of Medical Sciences and Sichuan Provincial Peoples Hospital โ Chengdu, Sichuan
- Hangzhou First Peoples Hospital โ Hangzhou, Zhejiang
- Taizhou Hospital of Zhejiang Province (East) โ Taizhou, Zhejiang
๐ Contact the Study Coordinator
Phone: (877) 828-5568
Email: clinicaltrials@beonemed.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression โ Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors โ Glendale, California
- QTX3046 in Patients With KRAS G12D Mutations โ Grand Rapids, Michigan
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors โ Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer โ Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors โ San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.