Phase 1a/1b First-in-Human Study of BG-C9074 Alone and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors (NCT06233942)
Phase 1a/1b Study of BG-C9074, an Antibody Drug Conjugate Targeting B7H4, as Monotherapy and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors
🩺 Plain-English Summary (8th-Grade Level)
This is a first-in-human, dose finding and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-C9074 alone and in combination with other anticancer therapies in patients with advanced solid tumors.
Who can join: Review the eligibility criteria below.
Location: Usc Norris Comprehensive Cancer Center (Nccc) — Los Angeles, California
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (37 Sites)
Showing the first 25 of 37 sites.
- Usc Norris Comprehensive Cancer Center (Nccc) — Los Angeles, California
- University of Colorado Cancer Center — Aurora, Colorado
- Florida Cancer Specialist Research Institute Lake Nona — Orlando, Florida
- Sidney Kimmel Comprehensive Cancer At Johns Hopkins — Baltimore, Maryland
- James Cancer Hospital and Solove Research Institute — Columbus, Ohio
- Blacktown Cancer and Haematology Centre — Blacktown, New South Wales
- Macquarie University — North Ryde, New South Wales
- Cancer Care Wollongong — Wollongong, New South Wales
- Princess Alexandra Hospital — Woolloongabba, Queensland
- Monash Health — Clayton, Victoria
- Cabrini Hospital Malvern — Malvern, Victoria
- Peter Maccallum Cancer Centre — Melbourne, Victoria
- Linear Clinical Research — Nedlands, Western Australia
- Hospital Sirio Libanes Brasilia — Brasília,
- Liga Norte Riograndene Contra O Cancer — Natal,
- Hospital Sao Lucas Da Pucrs — Porto Alegre,
- Instituto Nacional de Cancer Hospital Do Cancer Ii — Rio de Janerio,
- Fundacao Faculdade Regional de Medicina de Sao Jose Do Rio Preto — São José do Rio Preto,
- Icesp Instituto Do Cancer Do Estado de Sao Paulo Octavio Frias de Oliveira — São Paulo,
- Clinica de Pesquisa E Centro de Estudos Em Oncologia Ginecologica E Mamaria — São Paulo,
- Cancer Hospital Chinese Academy of Medical Sciences — Beijing, Beijing Municipality
- Fujian Cancer Hospital — Fuzhou, Fujian
- Sun Yat Sen University Cancer Center — Guangzhou, Guangdong
- Harbin Medical University Cancer Hospital — Harbin, Heilongjiang
- Union Hospital of Tongji Medical College, Huazhong University of Science and Technology — Wuhan, Hubei
📞 Contact the Study Coordinator
Phone: (877) 828-5568
Email: clinicaltrials@beonemed.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression — Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors — Glendale, California
- QTX3046 in Patients With KRAS G12D Mutations — Grand Rapids, Michigan
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors — Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer — Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors — San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.