A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors (NCT06244485)
A Phase 1b, Multicenter, Open-Label Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
This study will evaluate the safety, tolerability, and efficacy of valemetostat tosylate in combination with DXd ADC in patients with advanced solid tumors.
Who can join: Review the eligibility criteria below.
Location: City of Hope At Orange County Lennar Foundation Cancer Center โ Irvine, California
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (35 Sites)
Showing the first 25 of 35 sites.
- City of Hope At Orange County Lennar Foundation Cancer Center โ Irvine, California
- Sharp Memorial Hospital โ San Diego, California
- Brcr Medical Center, Inc Dba Boca Raton Clinical Research โ Plantation, Florida
- University of Hawaii At Manoa โ Honolulu, Hawaii
- University of Chicago Medical Center โ Chicago, Illinois
- Dana-Farber Cancer Institute โ Boston, Massachusetts
- Memorial Sloan-Kettering Cancer Center (Mskcc) - New York โ New York, New York
- Clinical Research Alliance โ Westbury, New York
- Unc Hospitals โ Chapel Hill, North Carolina
- The Cleveland Clinic Foundation โ Cleveland, Ohio
- Providence Portland Medical Center โ Portland, Oregon
- Mary Crowley Cancer Research Centers โ Dallas, Texas
- Ut Southwestern Medical Center โ Dallas, Texas
- University of Texas M. D. Anderson Cancer Center โ Houston, Texas
- Next Virginia โ Fairfax, Virginia
- Fred Hutchinson Cancer Center โ Seattle, Washington
- Medical College of Wisconsin โ Milwaukee, Wisconsin
- Peking University Third Hospital โ Beijing,
- Sun Yat-Sen University, Cancer Center โ Guangzhou,
- SunYat-Sen University Cancer Center โ Guangzhou,
- Harbin Medical Univeristy Cancer Hospital โ Heilongjiang,
- Hunan Cancer Hospital โ Hunan,
- Jilin Cancer Hospital โ Jilin City,
- Jinana Center Hosptial โ Shandong,
- IRCCS Istituto Scientifico Romagnolo Per โ Cesena,
๐ Contact the Study Coordinator
Phone: (800) 826-4673
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression โ Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors โ Glendale, California
- QTX3046 in Patients With KRAS G12D Mutations โ Grand Rapids, Michigan
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors โ Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer โ Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors โ San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.