πŸ›οΈ Verified NIH Record β€’ Updated 2026-03-09

First-in-human Study of Interferon-y PET Imaging to Assess Response to Immunotherapy (NCT06439914)

IFN-y PET Imaging: Bench to Bedside

🟒 Recruiting Phase1 πŸ’Š Investigational Drug / Biologic Sponsor: Nerissa T. Viola

🩺 Plain-English Summary (8th-Grade Level)

The goal of this clinical trial is to investigate the use of \[89Zr\]Zr-DFO-emapalumab as an IFN-Ξ³ PET imaging agent to detect lesions and response to therapy among treatment-naΓ―ve non-small cell lung cancer (NSCLC) patients. PET scans following the imaging agent will be completed prior to and about 30 days after starting immunotherapy.

Who can join: Review the eligibility criteria below.

Location: Karmanos Cancer Institute β€” Detroit, Michigan

Age range: 18 Years

πŸ§ͺ Interventions in This Study

πŸ“‹ "Do I Qualify?" β€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria β†—

πŸ“ All Participating Trial Locations (1 Sites)

  • Karmanos Cancer Institute β€” Detroit, Michigan

πŸ“ž Contact the Study Coordinator

Phone: (313) 576-8309

Email: violan@karmanos.org

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

πŸ’° Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA Β§ 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

πŸ’‘ How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
πŸ›οΈ View Official NIH Record β†—