Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors (NCT06545942)
A Phase 1 Study of MOMA-313 Given as Monotherapy or in Combination With a PARP Inhibitor in Participants With Advanced or Metastatic Solid Tumors
๐ฉบ Plain-English Summary (8th-Grade Level)
This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-313 administered orally as a single agent or combination therapy in patients with homologous recombinant deficient solid tumors.
Who can join: Review the eligibility criteria below.
Location: Investigative Site #108 โ Goodyear, Arizona
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (18 Sites)
- Investigative Site #108 โ Goodyear, Arizona
- Investigative Site #101 โ La Jolla, California
- Investigative Site #111 โ San Francisco, California
- Investigative Site #104 โ Lake Mary, Florida
- Investigative Site #110 โ St Louis, Missouri
- Investigative Site #103 โ New York, New York
- Investigative Site #106 โ New York, New York
- Investigative Site #109 โ Philadelphia, Pennsylvania
- Investigative Site #107 โ Myrtle Beach, South Carolina
- Investigative Site #102 โ Nashville, Tennessee
- Investigative Site #105 โ San Antonio, Texas
- Investigative Site #112 โ Fairfax, Virginia
- Investigative Site #114 โ Barcelona,
- Investigative Site #116 โ Barcelona,
- Investigative Site #115 โ Madrid,
- Investigative Site #113 โ London,
- Investigative Site #117 โ Manchester,
- Investigative Site #118 โ Newcastle upon Tyne,
๐ Contact the Study Coordinator
Phone: (857) 285-3677
Email: clinicaltrials@momatx.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression โ Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors โ Glendale, California
- QTX3046 in Patients With KRAS G12D Mutations โ Grand Rapids, Michigan
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors โ Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer โ Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors โ San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.