๐๏ธ Verified NIH Record โข Updated 2026-08-26
ARC101 in Advanced Solid Tumors (NCT06672185)
A Phase 1 Study of ARC101 in Advanced Solid Tumors
๐ข Recruiting Phase1 ๐ Investigational Drug / Biologic Sponsor: Third Arc Bio
๐ฉบ Plain-English Summary (8th-Grade Level)
This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of ARC101 in patients with advanced cancer.
Who can join: Review the eligibility criteria below.
Location: Massachusetts General Hospital โ Boston, Massachusetts
Age range: 18 Years
๐งช Interventions in This Study
๐ "Do I Qualify?" โ 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria โ
๐ All Participating Trial Locations (13 Sites)
- Massachusetts General Hospital โ Boston, Massachusetts
- START Midwest โ Grand Rapids, Michigan
- START San Antonio, LLC. โ San Antonio, Texas
- Sunshine Coast University Private Hospital โ Birtinya, Queensland
- Cancer Research SA โ Adelaide, South Australia
- Cabrini Health Research โ Malvern, Victoria
- BC Cancer Research Centre โ Vancouver, British Columbia
- The Princess Margaret Cancer Centre โ Toronto, Ontario
- Jewish General Hospital โ Montreal, Quebec
- McGill University Health Centre โ Montreal, Quebec
- Rambam Medical Center โ Haifa,
- Sheba Medical Center โ Ramat Gan,
- Sourasky Medical Center โ Tel Aviv,
๐ Contact the Study Coordinator
Phone: (267) 589-9444
Email: clinicaltrials@thirdarcbio.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
๐ฐ Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
More studies in Advanced Solid Tumor
- Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression โ Iowa City, Iowa
- A Phase 1/2 Study of OBI-992 in Subjects With Advanced Solid Tumors โ Glendale, California
- QTX3046 in Patients With KRAS G12D Mutations โ Grand Rapids, Michigan
- A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors โ Houston, Texas
- First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer โ Fullerton, California
- A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors โ San Antonio, Texas
Explore by condition: All Advanced Solid Tumor clinical trials
๐ก How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.