๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-02-25

A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1) (NCT06905197)

A Phase 1, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD6008 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations (TIAN-SHAN1)

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Dizal Pharmaceuticals

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This study is designed to evaluate safety and anti-tumor activity of DZD6008 in patients with advanced NSCLC with EGFR mutations.

Who can join: Review the eligibility criteria below.

Location: Laura and Isaac Perlmutter Cancer Center at NYU Langone Health โ€” New York, New York

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (5 Sites)

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone Health โ€” New York, New York
  • Herbert Irving Comprehensive Cancer Center โ€” New York, New York
  • Virginia Cancer Specialist (NEXT Oncology-Virginia) โ€” Fairfax, Virginia
  • Blacktown Hospital โ€” Blacktown, New South Wales
  • Chris O'Brien Lifehouse โ€” Camperdown, New South Wales

๐Ÿ“ž Contact the Study Coordinator

Phone: 86-21-61095854

Email: yifan.liu@dizalpharma.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—