Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors (NCT06974110)
A Phase 1 Study of MOMA-341 as Monotherapy or Combination Therapy in Participants With Advanced or Metastatic Solid Tumors
🩺 Plain-English Summary (8th-Grade Level)
This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-341 administered orally as a single agent or combination therapy in patients with microsatellite instability high (MSI-H) or DNA mismatch repair deficiency (dMMR) solid tumors.
Who can join: Review the eligibility criteria below.
Location: Investigative Site #132 — Phoenix, Arizona
Age range: 18 Years
🧪 Interventions in This Study
📋 "Do I Qualify?" — 1-Minute Self Screener
Instant ChecklistFull eligibility criteria are available on the official NIH protocol. View the criteria ↗
📍 All Participating Trial Locations (15 Sites)
- Investigative Site #132 — Phoenix, Arizona
- Investigative Site #101 — San Diego, California
- Investigative Site #128 — Tampa, Florida
- Investigative Site #120 — Detroit, Michigan
- Investigative Site #110 — St Louis, Missouri
- Investigative Site #131 — Raleigh, North Carolina
- Investigative Site #121 — Portland, Oregon
- Investigative Site #127 — Dallas, Texas
- Investigative Site #129 — Houston, Texas
- Investigative Site #122 — Sydney, New South Wales
- Investigative Site #123 — Westmead, New South Wales
- Investigative Site #124 — Woolloongabba, Queensland
- Investigative Site #125 — Adelaide, South Australia
- Investigative Site #126 — Clayton, Victoria
- Investigative Site #119 — Perth, Western Australia
📞 Contact the Study Coordinator
Phone: (857) 285-3677
Email: clinicaltrials@momatx.com
Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.
💰 Cost, Insurance & Patient Rights
- 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
- Routine Patient Care: Under federal law (ACA § 2709) and many state statutes, routine care costs are covered during participation.
- Voluntary Participation: You may withdraw at any time without affecting your standard medical care.
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💡 How to Participate
- Check the checklist above to see if you may qualify.
- Contact the study coordinator using the phone/email above.
- Ask about the visit schedule, what is covered at no cost, and any travel support.
- Confirm with your own doctor before making a decision.