๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-07-09

A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors (NCT06997029)

A Phase 1 First-in-human Study of BMS-986500 as Monotherapy in Advanced Solid Tumors and as Combination Therapy in CDK4/6 Inhibitor Pre-treated Advanced Breast Cancer

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: Bristol-Myers Squibb

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to assess BMS-986500 as monotherapy in advanced solid tumors and as combination therapy in CDK4/6 inhibitor pre-treated advanced breast cancer.

Who can join: Review the eligibility criteria below.

Location: University of Alabama at Birmingham โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (21 Sites)

  • University of Alabama at Birmingham โ€” Birmingham, Alabama
  • Providence St. Jude Medical Center โ€” Fullerton, California
  • Marin Cancer Care โ€” Greenbrae, California
  • Moores Cancer Center โ€” La Jolla, California
  • Hoag Memorial Hospital Presbyterian โ€” Newport Beach, California
  • Local Institution - 0008 โ€” Aurora, Colorado
  • Dana-Farber Cancer Institute โ€” Boston, Massachusetts
  • Washington University School of Medicine โ€” St Louis, Missouri
  • Dartmouth-Hitchcock Medical Center โ€” Lebanon, New Hampshire
  • Roswell Park Cancer Institute โ€” Buffalo, New York
  • Northwell Health-Cancer Institute โ€” New Hyde Park, New York
  • Local Institution - 0011 โ€” New York, New York
  • Memorial Sloan Kettering Cancer Center โ€” New York, New York
  • START Dallas Fort Worth โ€” Fort Worth, Texas
  • NEXT Oncology โ€” San Antonio, Texas
  • Odense Universitetshospital โ€” Odense, Region Syddanmark
  • Copenhagen University Hospital โ€” Copenhagen,
  • National Cancer Center Hospital East โ€” Kashiwa, Chiba
  • Kansai Medical University Hospital โ€” Hirakata, Osaka
  • National Cancer Center Hospital โ€” Chuo-ku, Tokyo
  • The Cancer Institute Hospital of JFCR โ€” Koto-ku, Tokyo

๐Ÿ“ž Contact the Study Coordinator

Phone: (855) 907-3286

Email: Clinical.Trials@bms.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—