๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2025-12-23

A Study of YL242 in Subjects With Advanced Solid Tumors (NCT07197827)

A Phase 1/2, Multicenter, Open-Label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of YL242 Monotherapy and Combinations in Advanced Solid Tumors.

๐ŸŸข Recruiting Phase1 / Phase2 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

This is a multicenter, open-label study to evaluate the safety and tolerability of YL242 monotherapy and combination in participants with advanced solid malignant tumors.

Who can join: Review the eligibility criteria below.

Location: US-201 โ€” New Haven, Connecticut

Age range: 18 Years

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (15 Sites)

  • US-201 โ€” New Haven, Connecticut
  • US-202 โ€” Sarasota, Florida
  • US-204 โ€” Boston, Massachusetts
  • US-206 โ€” Grand Rapids, Michigan
  • US-205 โ€” Nashville, Tennessee
  • US-203 โ€” Houston, Texas
  • US-207 โ€” San Antonio, Texas
  • AUS-101 โ€” Liverpool, New South Wales
  • AUS-102 โ€” Darlinghurst, Victoria
  • AUS-104 โ€” Fitzroy, Victoria
  • AUS-103 โ€” Heidelberg, Victoria
  • AUS-105 โ€” Nedlands, Western Australia
  • CN-303 โ€” Harbin, Heilongjiang
  • CN-301 โ€” Shanghai, Shanghai Municipality
  • CN-302 โ€” Hangzhou, Zhejiang

๐Ÿ“ž Contact the Study Coordinator

Phone: +86 0512-62858368

Email: clinicaltrials@medilinkthera.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—