๐Ÿ›๏ธ Verified NIH Record โ€ข Updated 2026-08-18

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors (NCT07226349)

A Phase 1a/1b, Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of BG-75098 Alone and in Combination With Other Agents in Patients With Advanced Solid Tumors

๐ŸŸข Recruiting Phase1 ๐Ÿ’Š Investigational Drug / Biologic Sponsor: BeOne Medicines

๐Ÿฉบ Plain-English Summary (8th-Grade Level)

The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-75098 alone and in combination with BGB-43395 and fulvestrant in participants with advanced solid tumors.

Who can join: Review the eligibility criteria below.

Location: University of Alabama At Birmingham Hospital โ€” Birmingham, Alabama

Age range: 18 Years

๐Ÿงช Interventions in This Study

๐Ÿ“‹ "Do I Qualify?" โ€” 1-Minute Self Screener

Instant Checklist

Full eligibility criteria are available on the official NIH protocol. View the criteria โ†—

๐Ÿ“ All Participating Trial Locations (22 Sites)

  • University of Alabama At Birmingham Hospital โ€” Birmingham, Alabama
  • Yale Cancer Center โ€” New Haven, Connecticut
  • Sidney Kimmel Comprehensive Cancer At Johns Hopkins โ€” Baltimore, Maryland
  • Massachusetts General Hospital โ€” Boston, Massachusetts
  • The University of Texas Md Anderson Cancer Center โ€” Houston, Texas
  • Next Houston โ€” Houston, Texas
  • Medical College of Wisconsin โ€” Milwaukee, Wisconsin
  • Blacktown Cancer and Haematology Centre โ€” Blacktown, New South Wales
  • Genesiscare St Leonards โ€” St Leonards, New South Wales
  • Icon Cancer Centre Wesley โ€” Auchenflower, Queensland
  • Cabrini Hospital Malvern โ€” Malvern, Victoria
  • Peter Maccallum Cancer Centre โ€” Melbourne, Victoria
  • One Clinical Research โ€” Nedlands, Western Australia
  • Cancer Hospital Chinese Academy of Medical Sciences โ€” Beijing, Beijing Municipality
  • Sun Yat Sen Memorial Hospital, Sun Yat Sen University (South) โ€” Guangzhou, Guangdong
  • Harbin Medical University Cancer Hospital โ€” Harbin, Heilongjiang
  • Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology โ€” Wuhan, Hubei
  • Union Hospital Tongji Medical College Huazhong University of Science and Technologyjinyinhu Branch โ€” Wuhan, Hubei
  • Jiangsu Province Hospital Longjiang Branch โ€” Nanjing, Jiangsu
  • Qilu Hospital of Shandong University โ€” Jinan, Shandong
  • Weifang Peoples Hospital โ€” Weifang, Shandong
  • Rigshospitalet โ€” Copenhagen,

๐Ÿ“ž Contact the Study Coordinator

Phone: (877) 828-5568

Email: clinicaltrials@beonemed.com

Coordinator details come directly from the registered NIH protocol. Confirm the study is still recruiting before traveling.

๐Ÿ’ฐ Cost, Insurance & Patient Rights

  • 100% Free Items: The investigational treatment and protocol-required procedures are supplied at zero cost by the sponsor.
  • Routine Patient Care: Under federal law (ACA ยง 2709) and many state statutes, routine care costs are covered during participation.
  • Voluntary Participation: You may withdraw at any time without affecting your standard medical care.

๐Ÿ’ก How to Participate

  1. Check the checklist above to see if you may qualify.
  2. Contact the study coordinator using the phone/email above.
  3. Ask about the visit schedule, what is covered at no cost, and any travel support.
  4. Confirm with your own doctor before making a decision.
๐Ÿ›๏ธ View Official NIH Record โ†—