100 Recruiting Studies at University Of Pennsylvania
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Philadelphia, Pennsylvania
All research centersRecruiting Studies at University Of Pennsylvania
🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
Alcohol Use Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Neuroinflammation Imaging in AD
Alzheimer Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism
Autism Spectrum Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Transportation Safety in Adolescence
Automobile Accident
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
BRCA1/2 Flu Vaccine
BRCA1 Mutation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
INO 5401 Vaccination in BRCA1/2 Mutation Carriers
BRCA1/2 Mutation
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Imaging of Primary or Recurrent Breast Cancer With 18F-FluorThanatrace PET/CT
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Using Diagnostic Tools to Stage Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care
Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Edema and Fibrosis CMR Imaging in Cardiomyopathy
Cardiomyopathies
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CART22 Alone or in Combination With huCART19 for ALL
Chemotherapy Resistant Acute Lymphoblastic Leukemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients
Chronic Insomnia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
huCART19-IL18 in CD19+ Cancers
Chronic Lymphocytic Leukemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Clavulanic Acid for the Treatment of Cocaine Use Disorder
Cocaine Dependence
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Reducing Fatigue With CoQ10 Supplementation in Patients With Crohn's Disease Study
Crohn Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Evaluation of D3 Receptor Occupancy Using FLUORTRIOPRIDE ([18F]FTP) PET/CT
D3 Dopamine Receptor
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Light Therapy in End Stage Kidney Disease
End Stage Renal Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Penn Medicine Biobank Return of Results Program
Genetic Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
Effects of Sitagliptin in Individuals With Genetically Decreased DPP4
Genetics Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy
Glioblastoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM
Glioblastoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CD40 Agonist and PD-1 Inhibitor in HNSCC
Head and Neck Squamous Cell Carcinoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
PennPET Explorer Scanner Evaluation
Healthy
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Early Metabolic Adaptations to SGLT2 Inhibition in Heart Failure
Heart Failure NYHA Class II
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CD4 CAR+ ZFN-modified T Cells in HIV Therapy
Hiv
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Evaluation of Neuroinflammation FNOS PET/CT in HIV (+) and (-) Subjects With OUD and Healthy Controls
HIV Infections
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Gamification and Medication Adherence (GAME Adherence)
Hypertension and Hyperlipidemia
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Intravenous Estrogen in Kidney Transplant Study
Ischemia Reperfusion Injury
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Implementation Strategies for Monitoring Adherence in Real Time
Lung Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial
Mayer Rokitansky Kuster Hauser Syndrome
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
GFRα4 CAR T Cells in MTC Patients
Metastatic Medullary Thyroid Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Migraine and CVD Risk in Women
Migraine
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma
Myeloma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
TmCD19-IL18 in CD19+ Cancers
Non Hodgkin Lymphoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase2 💊 Investigational Drug / Biologic
Abemaciclib in Patients with Oligodendroglioma
Oligodendroglioma, Adult
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement
Opioid Use Disorder
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Nudge to Gynecologic Oncology
Ovarian Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
huCART-meso + VCN-01 in Pancreatic and Ovarian Cancer
Pancreatic Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Evaluating a Strengths-based Community-grounded Intervention
Parenting
View Study & Checklist ➔ 🔵 Active, Not Recruiting Early Phase1 💊 Investigational Drug / Biologic
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
Parkinson Disease
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
Primary Graft Dysfunction
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Leveraging EA8191 to Assess AI-Augmented EHR Abstraction
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CART-PSMA-TGFβRDN Cells for Castrate-Resistant Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer
Prostate Cancer
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Psoriatic Arthritis D2P Screening
Psoriatic Arthritis
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM
Recurrent Glioblastoma
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
CART123 + Ruxolitinib in Relapsed/Refractory AML
Relapsed AML
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase1 💊 Investigational Drug / Biologic
Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction
Smoking, Tobacco
View Study & Checklist ➔ 🔵 Active, Not Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Mobility and Voiding Exercises in Older Women With Urinary Incontinence (MoVEonUp)
Urinary Incontinence, Urge
View Study & Checklist ➔ 🔵 Active, Not Recruiting Phase4 💊 Investigational Drug / Biologic
Flu Vaccine Responses in the Setting of Melanoma Treatment
Viral Vaccines
View Study & Checklist ➔ 🔵 Active, Not Recruiting Interventional Protocol 📊 Observational Clinical Research
Vaccine Responses in Cancer
Viral Vaccines
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Effect of cTBS on Startle and TMS-evoked BOLD
Anxiety
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase4 💊 Investigational Drug / Biologic
Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis
Axial Spondylarthritis (axSpA)
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Partial Enteral Nutrition as Therapeutic Augmentation of Advanced Pharmacological Therapy in Patients With Active Crohn's Disease
Crohn's Disease, Active
View Study & Checklist ➔ 🟡 Not Yet Recruiting Phase2 💊 Investigational Drug / Biologic
OT-101 in Combination With Pembrolizumab in Subjects With Malignant Pleural Mesothelioma Failing to Respond to Checkpoint Inhibition
Malignant Pleural Mesothelioma
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase
Opioid Use Disorder
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention
Opioid Use Disorder
View Study & Checklist ➔ 🟡 Not Yet Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Evaluating the Preferences and Tradeoffs of AI-based Electronic Consultations for Older Adults in Primary Care
Primary Care Patients
View Study & Checklist ➔ 🟢 Recruiting Phase2 ⚙️ Medical Device Protocol
Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
Aphasia
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
Autism
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
CD45BE-HSPC + CART-45 Cells
B-Cell Non-Hodgkin Lymphoma (NHL)
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjects
Bacterial Infections
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Prospective 4D CTA of BAV Competence
Bicuspid
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic ⚙️ Medical Device Protocol
Resting State Changes Following Theta Burst Stimulation
Brain Connectivity
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
[18F] F-GLN by PET/CT in Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
FES BPET-DBT in Newly Diagnosed Breast Cancer
Breast Cancer
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Reducing Patient Memory Recall in the Burning Mouth Patient Population
Burning Mouth Syndrome
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression
Cardiac Sarcoidosis
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
International Registry for Patients With Castleman Disease
Castleman Disease
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease
Castleman's Disease (CD)
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Short Course Radiotherapy
Central Nervous System Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana
Cervical Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
TCR1188-ABC Cells in KRAS-mutated Cancers
Cholangiocarcinoma
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Click & Pick Study
Chronic Disease
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit
Cigarette Smoking
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Menstrual Cycle TMS Plasticity Pilot
Cortical Activation
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
Tadekinig Alfa (IL-18BP) Rescue Therapy for CAR T Cell Related Cytokine Release Syndrome (CRS) and HLH-like Syndrome
CRS - Cytokine Release Syndrome
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Philly CEAL- DECIDE+ Adaptation
Disparities
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers
E-cigarette Use
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Integrating Telehealth to Advance Lung Cancer Screening
Early Detection of Cancer
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer
Early Stage Non-Small Cell Lung Cancer
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Virtual Reality in End Stage Kidney Disease
End Stage Kidney Disease
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 📋 Clinical Research Protocol
Localizing Epileptic Networks Using MRI and iEEG
Epilepsy
View Study & Checklist ➔ 🟢 Recruiting Phase1 💊 Investigational Drug / Biologic
FAPI-74 PET/CT in Adults With Fibrosis
Fibrosis (Morphologic Abnormality)
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
UPenn Observational Research Repository on Neurodegenerative Disease
Frontotemporal Degeneration(FTD)
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma
Glioma
View Study & Checklist ➔ 🟢 Recruiting Phase1 / Phase2 💊 Investigational Drug / Biologic
Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging
Healthy
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Matching Perfusion and Metabolic Activity in HFpEF
Heart Failure With Preserved Ejection Fraction
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
Transitional Housing and HIV Health
HIV
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Streamlining Telehealth for Expanded PrEP Utilization Through Community Partnerships
HIV
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Enhancing the Organizational Social Context to Improve Viral Suppression and Retention in HIV Care
HIV/AIDS
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 🧠 Behavioral & Psychological Program
Intervention to Improve Parent Communication About Sexuality
HIV/STI Incidence
View Study & Checklist ➔ 🟢 Recruiting Interventional Protocol 📊 Observational Clinical Research
HoFH, the International Clinical Collaborators Registry
Homozygous Familial Hypercholesterolemia
View Study & Checklist ➔ 🟢 Recruiting Early Phase1 💊 Investigational Drug / Biologic
Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy Without Obstruction
View Study & Checklist ➔ 🟢 Recruiting Observational / Diagnostic 📋 Clinical Research Protocol
Physiological Effects of ANGPTL3 Variants in Humans
Hypocholesterolemia
View Study & Checklist ➔ 🟢 Recruiting Phase2 💊 Investigational Drug / Biologic
Duloxetine in Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
Characterization of Humoral and Cellular Immune Responses Elicited by Influenza Vaccination in Healthy Adults
Influenza, Human
View Study & Checklist ➔ 🟢 Recruiting Phase4 💊 Investigational Drug / Biologic
A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
Insomnia
View Study & Checklist ➔