100 Recruiting Studies at University Of Alabama At Birmingham Cancer Center
Active clinical trials at this research center, sourced directly from the NIH registry.
📍 Birmingham, Alabama
All research centersRecruiting Studies at University Of Alabama At Birmingham Cancer Center
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
Acinar Cell Carcinoma
View Study & Checklist ➔A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma
Acral Lentiginous Melanoma
View Study & Checklist ➔Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia
View Study & Checklist ➔Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia
View Study & Checklist ➔Testing Nivolumab to Prevent Disease From Coming Back After Treatment in Patients With Acute Myeloid Leukemia, REMAIN Trial
Acute Myeloid Leukemia
View Study & Checklist ➔BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia
Acute Myeloid Leukemia
View Study & Checklist ➔Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients
Acute Myeloid Leukemia
View Study & Checklist ➔Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas
Adult Anaplastic Astrocytoma
View Study & Checklist ➔Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)
Advanced Biliary Tract Carcinoma
View Study & Checklist ➔Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer
Advanced Cervical Adenocarcinoma
View Study & Checklist ➔Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma
Advanced Dedifferentiated Liposarcoma
View Study & Checklist ➔Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer
Advanced Lung Non-Small Cell Carcinoma
View Study & Checklist ➔Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
Advanced Lymphoma
View Study & Checklist ➔Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)
Advanced Malignant Solid Neoplasm
View Study & Checklist ➔Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study
Advanced Malignant Solid Neoplasm
View Study & Checklist ➔Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Advanced Melanoma
View Study & Checklist ➔Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study
Advanced Renal Cell Carcinoma
View Study & Checklist ➔Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer
Advanced Triple-Negative Breast Carcinoma
View Study & Checklist ➔Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers
Advanced Vaginal Adenocarcinoma
View Study & Checklist ➔Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)
ALK Gene Rearrangement
View Study & Checklist ➔Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer
Anal Basaloid Carcinoma
View Study & Checklist ➔Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study
Anal Basaloid Carcinoma
View Study & Checklist ➔Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma
Anaplastic Astrocytoma
View Study & Checklist ➔Additional Support Program Via Text Messaging and Telephone-Based Counseling for Breast Cancer Patients Receiving Hormonal Therapy
Anatomic Stage I Breast Cancer AJCC v8
View Study & Checklist ➔Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer
Anatomic Stage I Breast Cancer AJCC v8
View Study & Checklist ➔T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
Anatomic Stage II Breast Cancer AJCC v8
View Study & Checklist ➔Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial
Anatomic Stage II Breast Cancer AJCC v8
View Study & Checklist ➔CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
Anatomic Stage II Breast Cancer AJCC v8
View Study & Checklist ➔Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic
Anatomic Stage III Breast Cancer AJCC v8
View Study & Checklist ➔Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8
View Study & Checklist ➔Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones
Anatomic Stage IV Breast Cancer AJCC v8
View Study & Checklist ➔Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study
Anatomic Stage IV Breast Cancer AJCC v8
View Study & Checklist ➔Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer
Anatomic Stage IV Breast Cancer AJCC v8
View Study & Checklist ➔Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia
Anemia
View Study & Checklist ➔Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Anemia
View Study & Checklist ➔Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin Lymphoma
Ann Arbor Stage I Hodgkin Lymphoma
View Study & Checklist ➔Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic Leukemia
B Acute Lymphoblastic Leukemia
View Study & Checklist ➔Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
View Study & Checklist ➔De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
Basaloid Squamous Cell Carcinoma
View Study & Checklist ➔Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer
Bladder Flat Urothelial Carcinoma In Situ
View Study & Checklist ➔Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine With or Without Bevacizumab as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II-IV or Recurrent Stage I Epithelial Ovarian or Fallopian Tube Cancer
Borderline Ovarian Mucinous Tumor
View Study & Checklist ➔Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma
BRAF V600E Mutation Present
View Study & Checklist ➔Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma
Brain and Central Nervous System Tumors
View Study & Checklist ➔Understanding and Predicting Breast Cancer Events After Treatment
Breast Cancer
View Study & Checklist ➔S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Breast Cancer
View Study & Checklist ➔Higher Per Daily Treatment-Dose Radiation Therapy or Standard Per Daily Treatment Radiation Therapy in Treating Patients With Early-Stage Breast Cancer That Was Removed by Surgery
Breast Cancer
View Study & Checklist ➔Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
Breast Carcinoma In Situ
View Study & Checklist ➔Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer
Breast Screening
View Study & Checklist ➔Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer
Cervical Adenocarcinoma
View Study & Checklist ➔Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S01)
Cervical Carcinoma
View Study & Checklist ➔Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S02)
Cervical Carcinoma
View Study & Checklist ➔Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
View Study & Checklist ➔Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
View Study & Checklist ➔Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia
Chronic Myelomonocytic Leukemia
View Study & Checklist ➔Dabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 Melanoma
Clinical Stage III Cutaneous Melanoma AJCC v8
View Study & Checklist ➔Physician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by Surgery
Clinical Stage III Cutaneous Melanoma AJCC v8
View Study & Checklist ➔Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery
Colon Adenocarcinoma
View Study & Checklist ➔Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer
Colorectal Adenocarcinoma
View Study & Checklist ➔S0820, Adenoma and Second Primary Prevention Trial
Colorectal Neoplasms
View Study & Checklist ➔NCI COVID-19 in Cancer Patients, NCCAPS Study
COVID-19 Infection
View Study & Checklist ➔Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas
Diffuse Large B-Cell Lymphoma
View Study & Checklist ➔Lenalidomide and Dexamethasone With or Without Thalidomide in Treating Patients With Multiple Myeloma
DS Stage I Multiple Myeloma
View Study & Checklist ➔Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA
EBV Infection
View Study & Checklist ➔Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
Endometrial Adenocarcinoma
View Study & Checklist ➔Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer
Endometrial Clear Cell Adenocarcinoma
View Study & Checklist ➔Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer
Endometrial Endometrioid Adenocarcinoma
View Study & Checklist ➔Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery
Estrogen Receptor-positive Breast Cancer
View Study & Checklist ➔Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial
Exocrine Pancreas Carcinoma
View Study & Checklist ➔S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer
Extensive Stage Lung Small Cell Carcinoma
View Study & Checklist ➔Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer
Fallopian Tube Clear Cell Adenocarcinoma
View Study & Checklist ➔Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Fallopian Tube Clear Cell Adenocarcinoma
View Study & Checklist ➔Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Fallopian Tube Endometrioid Adenocarcinoma
View Study & Checklist ➔Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Glioblastoma
View Study & Checklist ➔Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Glioblastoma
View Study & Checklist ➔Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery
Head and Neck Cancer
View Study & Checklist ➔FES PET/CT in Predicting Response in Patients With Newly Diagnosed Metastatic Breast Cancer Receiving Endocrine Therapy
HER2/Neu Negative
View Study & Checklist ➔Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer
Human Papilloma Virus Infection
View Study & Checklist ➔Preventive Human Papillomavirus (HPV) Vaccine Trial in Kidney Transplant Recipients
Human Papillomavirus Infection
View Study & Checklist ➔Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)
Limited Stage Lung Small Cell Carcinoma
View Study & Checklist ➔Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer
Localized Renal Pelvis and Ureter Urothelial Carcinoma
View Study & Checklist ➔Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer
Locally Advanced Bladder Urothelial Carcinoma
View Study & Checklist ➔Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial
Locally Advanced Malignant Solid Neoplasm
View Study & Checklist ➔Testing the Addition of an Anti-Cancer Drug, Irinotecan, to the Standard Chemotherapy Treatment (FOLFOX) After Long-Course Radiation Therapy for Advanced-Stage Rectal Cancers to Improve the Rate of Complete Response and Long-Term Rates of Organ Preservation
Locally Advanced Rectal Carcinoma
View Study & Checklist ➔Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working
Locally Advanced Uterine Corpus Leiomyosarcoma
View Study & Checklist ➔Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma
Locally Recurrent Head and Neck Squamous Cell Carcinoma
View Study & Checklist ➔Comparison of Different Types of Surgery in Treating Patients With Stage IA Non-Small Cell Lung Cancer
Lung Cancer
View Study & Checklist ➔Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
Lung Non-Small Cell Carcinoma
View Study & Checklist ➔Erlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial)
Lung Non-Squamous Non-Small Cell Carcinoma
View Study & Checklist ➔Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors
Malignant Solid Neoplasm
View Study & Checklist ➔Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
Mantle Cell Lymphoma
View Study & Checklist ➔Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery
Melanoma of Unknown Primary
View Study & Checklist ➔Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors
Metastatic Large Cell Neuroendocrine Carcinoma
View Study & Checklist ➔Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer
Metastatic Lung Non-Small Cell Carcinoma
View Study & Checklist ➔Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease
Metastatic Malignant Neoplasm in the Brain
View Study & Checklist ➔Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial
Metastatic Malignant Solid Neoplasm
View Study & Checklist ➔Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread
Metastatic Pancreatic Adenocarcinoma
View Study & Checklist ➔Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
Metastatic Renal Cell Carcinoma
View Study & Checklist ➔Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study
Metastatic Renal Cell Carcinoma
View Study & Checklist ➔Intravesical BCG vs GEMDOCE in NMIBC
Non-muscle-invasive Bladder Cancer
View Study & Checklist ➔Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer
Pancreatic Adenocarcinoma
View Study & Checklist ➔