100 Recruiting Studies at Research Site
Active clinical trials at this research center, sourced directly from the NIH registry.
π Duarte, California
All research centersRecruiting Studies at Research Site
Ascending Doses of Ceralasertib in Combination With Chemotherapy and/or Novel Anti Cancer Agents
Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer
View Study & Checklist βStudy of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
Advanced Cancer
View Study & Checklist βA Study of AB801 Monotherapy and Combination Therapy in Participants With Advanced Malignancies
Advanced Cancer
View Study & Checklist βA Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer
Advanced ER-Positive HER2-Negative Breast Cancer
View Study & Checklist βDurvalumab and Tremelimumab as First Line Treatment in Participants With Advanced Hepatocellular Carcinoma (HCC)
Advanced Hepatocellular Carcinoma
View Study & Checklist βAZD9291 in Combination With Ascending Doses of Novel Therapeutics
Advanced Non Small Cell Lung Cancer
View Study & Checklist βStudy of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer
Advanced or Metastatic Breast Cancer
View Study & Checklist βA Phase III Study of Ceralasertib Plus Durvalumab Versus Docetaxel in Patients With Non Small Cell Lung Cancer (NSCLC) Whose Disease Progressed On or After Prior Anti PD (L)1 Therapy And Platinum Based Chemotherapy
Advanced or Metastatic Non-Small Cell Lung Cancer
View Study & Checklist βPhase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer
Advanced or Metastatic NSCLC
View Study & Checklist βDurvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients
Advanced Ovarian Cancer
View Study & Checklist βA Study to Evaluate the Safety and Tolerability of AB680 in Participants With Gastrointestinal Malignancies
Advanced Pancreatic Cancer
View Study & Checklist βA Study to Evaluate MEDI5752 and Axitinib in Subjects With Advanced Renal Cell Carcinoma
Advanced Renal Cell Carcinoma
View Study & Checklist βA Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours
Advanced Solid Tumor
View Study & Checklist βA Study of Durvalumab (MEDI4736) and Monalizumab in Solid Tumors
Advanced Solid Tumors
View Study & Checklist βA Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations
Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast
View Study & Checklist βFirst in Human Study of AZD9592 in Solid Tumors
Advanced Solid Tumours
View Study & Checklist βA Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body
Advanced Upper Gastrointestinal Tract Adenocarcinoma
View Study & Checklist βA Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)
AL Amyloidosis
View Study & Checklist βA Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
AL Amyloidosis
View Study & Checklist βPhase 2 Study of ALXN2030 in Patients With Antibody-Mediated Rejection After Kidney Transplantation
Antibody-Mediated Rejection
View Study & Checklist βA Multicentre, Randomised, Double-blind, Parallel Group, Placebo-controlled, Time-to-first Asthma Exacerbation Phase III Efficacy and Safety Study of Benralizumab in Paediatric Patients With Severe Eosinophilic Asthma
Asthma
View Study & Checklist βCombination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care
Asthma
View Study & Checklist βBenralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
Asthma
View Study & Checklist βA Study to Investigate the Effect on Lung Function of BDA Formulated With a Next Generation Propellant Compared With an Approved Asthma Treatment (BDA With HFA Propellant) in Participants With Asthma
Asthma
View Study & Checklist βA Study of AZD0486 in Subjects With B-Cell Non-Hodgkin Lymphoma
B-cell Non Hodgkin Lymphoma
View Study & Checklist βRilvegostomig + Chemotherapy as Adjuvant Therapy for Biliary Tract Cancer After Resection (ARTEMIDE-Biliary01)
Biliary Tract Cancer
View Study & Checklist βDurvalumab With Chemotherapy as First Line Treatment in Patients With Advanced Biliary Tract Cancers (aBTCs)
Biliary Tract Cancer
View Study & Checklist βDurvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1)
Biliary Tract Neoplasms
View Study & Checklist βRT-310 Safety and Feasibility BPH Study
BPH (Benign Prostatic Hyperplasia)
View Study & Checklist βA Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)
Breast Cancer
View Study & Checklist βA Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)
Breast Cancer
View Study & Checklist βOlaparib as Adjuvant Treatment in Patients With Germline BRCA Mutated High Risk HER2 Negative Primary Breast Cancer
Breast Cancer
View Study & Checklist βA Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer
Breast Cancer
View Study & Checklist βA Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)
Breast Cancer
View Study & Checklist βStudy of Neoadjuvant Olaparib Monotherapy and Olaparib and Durvalumab Combination in HER2 Negative BRCAm Breast Cancer
Breast Cancer
View Study & Checklist βComparison of Fulvestrant (FASLODEXβ’) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy.
Breast Cancer
View Study & Checklist βA Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer
Breast Cancer
View Study & Checklist βAn Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2)
Breast Cancer, Early Breast Cancer
View Study & Checklist βTrastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)
Breast Cancer; HER2-positive; Metastatic
View Study & Checklist βTrastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer
Breast Neoplasms
View Study & Checklist βA Study to Learn About Study Medicine ALTA2618 in Adults With AKT1 E17K-Mutant Solid Tumors
Cancer
View Study & Checklist βSavolitinib Plus Osimertinib Versus Platinum-based Doublet Chemotherapy in Participants With Non-Small Cell Lung Cancer Who Have Progressed on Osimertinib Treatment
Carcinoma
View Study & Checklist βOsimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior Osimertinib
Carcinoma
View Study & Checklist βSavolitinib vs. Sunitinib in MET-driven PRCC.
Carcinoma
View Study & Checklist βOleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
Carcinoma, Non-Small-Cell Lung
View Study & Checklist βA Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients
Carcinoma, Non-Small-Cell Lung
View Study & Checklist βDurvalumab With Stereotactic Body Radiation Therapy (SBRT) vs Placebo With SBRT in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients/ Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR Mutation
Carcinoma, Non-Small-Cell Lung
View Study & Checklist βA Study to Investigate the Efficacy of Durvalumab Plus Tremelimumab in Combination With Chemotherapy Compared With Pembrolizumab in Combination With Chemotherapy in Metastatic NSCLC Patients With Non-squamous Histology Who Have Mutations and/or Co-mutations in STK11, KEAP1, or KRAS
Carcinoma, Non-Small-Cell Lung
View Study & Checklist βA Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer
Carcinoma, Non-Small-Cell Lung
View Study & Checklist βA Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM)
Cardiomyopathy, Dilated
View Study & Checklist βA Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD1705 in Participants With Dyslipidemia
Cardiovascular
View Study & Checklist βA Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event
Cardiovascular Disease
View Study & Checklist βA Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
Chronic Kidney Disease and Hypertension
View Study & Checklist βStudy to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria)
Chronic Kidney Disease With High Proteinuria
View Study & Checklist βA Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL
Chronic Lymphocytic Leukemia
View Study & Checklist βStudy of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)
Chronic Lymphocytic Leukemia
View Study & Checklist βStudy of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Chronic Lymphocytic Leukemia
View Study & Checklist βAcalabrutinib, Obinutuzumab and Chlorambucil in Treatment naΓ―ve CLL
Chronic Lymphocytic Leukemia
View Study & Checklist βA Study of ACP-196 (Acalabrutinib) in Subjects With Relapsed/Refractory CLL and Intolerant of Ibrutinib Therapy
Chronic Lymphocytic Leukemia
View Study & Checklist βACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia
Chronic Lymphocytic Leukemia
View Study & Checklist βAcalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia
View Study & Checklist βA Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
View Study & Checklist βA Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab
Chronic Rhinosinusitis With Nasal Polyps
View Study & Checklist βA Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
Cutaneous Lupus Erythematosus
View Study & Checklist βA Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
Diffuse Large B-Cell Lymphoma
View Study & Checklist βEfficacy, Safety and Tolerability of AZD6234 in Participants Living With Overweight or Obesity With Type 2 Diabetes Who Are on a Stable Dose of GLP-1 Receptor Agonist
Endocrinology
View Study & Checklist βDurvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer
Endometrial Neoplasms
View Study & Checklist βEfficacy and Safety of Tezepelumab in Patients With Eosinophilic Esophagitis
Eosinophilic Esophagitis
View Study & Checklist βEfficacy and Safety of Benralizumab in EGPA Compared to Mepolizumab.
Eosinophilic Granulomatous Vasculitis
View Study & Checklist βStudy of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.
ER+ HER2- Advanced Breast Cancer
View Study & Checklist βA Comparative Study of AZD9833 Plus Palbociclib Versus Anastrozole Plus Palbociclib in Patients With ER-Positive HER2 Negative Breast Cancer Who Have Not Received Any Systemic Treatment for Advanced Disease
ER-Positive HER2-Negative Breast Cancer
View Study & Checklist βPhase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
ER-Positive HER2-Negative Breast Cancer
View Study & Checklist βEndoscopic Evidence of Maintenance of Healing With Oral NEXIUM in Patients 1 to 11 Years Old With Erosive Esophagitis.
Erosive Esophagitis
View Study & Checklist βStudy of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC
Esophageal Squamous Cell Carcinoma
View Study & Checklist βPh1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
Gastric Cancer
View Study & Checklist βStudy for AZD4360 in Participants With Advanced Solid Tumours
Gastric Cancer
View Study & Checklist βAZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2
Gastric Cancer
View Study & Checklist βAssessing Durvalumab and FLOT Chemotherapy in Resectable Gastric and Gastroesophageal Junction Cancer
Gastrointestinal Neoplasms
View Study & Checklist βA Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies
Gastrointestinal Tract Malignancies
View Study & Checklist βSafety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
View Study & Checklist βEvaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis
Generalized Myasthenia Gravis
View Study & Checklist βA Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM)
Glioblastoma Multiforme
View Study & Checklist βA Phase I, Cross-over Study Comparing the Relative Bioavailability of Laroprovstat Plus Ezetimibe Fixed Combination Drug Products Versus Their Single Therapy Products in Healthy Adults
Healthy Participants
View Study & Checklist βA Study to Investigate the Effect of Elecoglipron on Rosuvastatin and Atorvastatin in Healthy Participants
Healthy Participants
View Study & Checklist βA Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma
Hepatocellular Carcinoma
View Study & Checklist βStudy of Durvalumab and Tremelimumab as First-line Treatment in Patients With Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma
View Study & Checklist βAssess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
Hepatocellular Carcinoma
View Study & Checklist βA Study of Durvalumab or Tremelimumab Monotherapy, or Durvalumab in Combination With Tremelimumab or Bevacizumab in Advanced Hepatocellular Carcinoma
Hepatocellular Carcinoma
View Study & Checklist βA Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma
Hepatocellular Carcinoma
View Study & Checklist βStudy of Novel Immunomodulators as Monotherapy and in Combination With Anticancer Agents in Participants With Advanced Hepatobiliary Cancer
Hepatocellular Carcinoma
View Study & Checklist βEvaluate Durvalumab and Tremelimumab +/- Lenvatinib in Combination With TACE in Patients With Locoregional HCC
Hepatocellular Carcinoma
View Study & Checklist βA US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE
Hepatocellular Carcinoma (HCC)
View Study & Checklist βARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
HER2 Positive Metastatic Breast Cancer
View Study & Checklist βA Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With HeFH
Heterozygous Familial Hypercholesterolaemia
View Study & Checklist βCapivasertib+Abiraterone as Treatment for Patients With Metastatic Hormone-sensitive Prostate Cancer and PTEN Deficiency
Hormone-Sensitive Prostate Cancer
View Study & Checklist βA Phase III Study to Evaluate the Efficacy and Safety of Benralizumab in Patients With Hypereosinophilic Syndrome (HES)
Hypereosinophilic Syndrome
View Study & Checklist βPhase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa
Hypophosphatasia
View Study & Checklist βPhase 3 Study of ALXN1850 in Treatment-NaΓ―ve Pediatric Participants With HPP
Hypophosphatasia
View Study & Checklist βPhase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa
Hypophosphatasia
View Study & Checklist βA Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)
Idiopathic Pulmonary Fibrosis
View Study & Checklist β